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Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues

The relative contribution of peripheral and central leptin signalling to the regulation of metabolism and the mechanisms through which leptin affects glucose homeostasis have not been fully elucidated. We generated complementary lines of mice with either leptin receptor (Lepr) knockdown or reconstit...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Pereira, Sandra, O’Dwyer, Shannon M., Webber, Travis D., Baker, Robert K., So, Victor, Ellis, Cara E., Yoon, Ji Soo, Mojibian, Majid, Glavas, Maria M., Karunakaran, Subashini, Clee, Susanne M., Covey, Scott D., Kieffer, Timothy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397253/
https://ncbi.nlm.nih.gov/pubmed/30824713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39498-3
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