Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues

The relative contribution of peripheral and central leptin signalling to the regulation of metabolism and the mechanisms through which leptin affects glucose homeostasis have not been fully elucidated. We generated complementary lines of mice with either leptin receptor (Lepr) knockdown or reconstit...

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Udgivet i:Sci Rep
Main Authors: Pereira, Sandra, O’Dwyer, Shannon M., Webber, Travis D., Baker, Robert K., So, Victor, Ellis, Cara E., Yoon, Ji Soo, Mojibian, Majid, Glavas, Maria M., Karunakaran, Subashini, Clee, Susanne M., Covey, Scott D., Kieffer, Timothy J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397253/
https://ncbi.nlm.nih.gov/pubmed/30824713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39498-3
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