Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations

Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Leal, Letícia Ferro, de Paula, Flávia Escremim, De Marchi, Pedro, de Souza Viana, Luciano, Pinto, Gustavo Dix Junqueira, Carlos, Carolina Dias, Berardinelli, Gustavo Noriz, Miziara, José Elias, da Silva, Carlos Maciel, Silva, Eduardo Caetano Albino, Pereira, Rui, de Oliveira, Marco Antonio, Scapulatempo-Neto, Cristovam, Reis, Rui Manuel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397232/
https://ncbi.nlm.nih.gov/pubmed/30824880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39965-x
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