Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations

Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KR...

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Foilsithe in:Sci Rep
Main Authors: Leal, Letícia Ferro, de Paula, Flávia Escremim, De Marchi, Pedro, de Souza Viana, Luciano, Pinto, Gustavo Dix Junqueira, Carlos, Carolina Dias, Berardinelli, Gustavo Noriz, Miziara, José Elias, da Silva, Carlos Maciel, Silva, Eduardo Caetano Albino, Pereira, Rui, de Oliveira, Marco Antonio, Scapulatempo-Neto, Cristovam, Reis, Rui Manuel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397232/
https://ncbi.nlm.nih.gov/pubmed/30824880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39965-x
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