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Length doesn't matter—telomere damage triggers cellular senescence in the ageing heart

Telomere shortening induces cellular senescence in proliferative cells. Yet, it is presently unclear how it is triggered in post‐mitotic cells such as cardiac myocytes. A new study by Anderson et al (2019) reports that during ageing of the heart, cellular senescence develops independently of telomer...

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Bibliografiske detaljer
Udgivet i:EMBO J
Hovedforfatter: Brand, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396151/
https://ncbi.nlm.nih.gov/pubmed/30770342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101571
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