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Length doesn't matter—telomere damage triggers cellular senescence in the ageing heart

Telomere shortening induces cellular senescence in proliferative cells. Yet, it is presently unclear how it is triggered in post‐mitotic cells such as cardiac myocytes. A new study by Anderson et al (2019) reports that during ageing of the heart, cellular senescence develops independently of telomer...

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Опубликовано в: :EMBO J
Главный автор: Brand, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396151/
https://ncbi.nlm.nih.gov/pubmed/30770342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101571
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