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Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges
Lynch syndrome (LS) is an autosomal dominant genetic disorder associated with germline mutations in DNA mismatch repair (MMR) genes. The carriers of pathogenic mutations in these genes have an increased risk of developing a colorectal cancer and/or LS-associated cancer. The LS-associated cancer type...
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6396136/ https://ncbi.nlm.nih.gov/pubmed/30867733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.9945 |
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