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Novel 2-(5-Imino-5H-isoquinolones[3,4-b]quinoxalin-7-ylmethyl)-benzonitrile (DIQ3) and Other Related Derivatives Targeting Colon Cancer Cells: Syntheses and in Vitro Models

[Image: see text] Chemotherapy has been shown to be effective in reducing the progression and development of cancer in metastatic patients. However, drug selectivity is still a major issue for most chemotherapeutics. In this study, we synthesized four novel heterocyclic compounds having similarity i...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Monzer, Alissar, Jabotian, Nayri, Ballout, Farah, Zhu, Jie S., Kurth, Mark J., Haddadin, Makhluf J., Gali-Muhtasib, Hala
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396124/
https://ncbi.nlm.nih.gov/pubmed/30842984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b02698
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