Cycling Quiescence in Temozolomide Resistant Glioblastoma Cells Is Partly Explained by microRNA-93 and -193-Mediated Decrease of Cyclin D

Glioblastoma multiforme (GBM) is a fatal malignancy of the central nervous system, commonly associated with chemoresistance. The alkylating agent Temozolomide (TMZ) is the front-line chemotherapeutic agent and has undergone intense studies on resistance. These studies reported on mismatch repair gen...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Munoz, Jessian L., Walker, Nykia D., Mareedu, Satvik, Pamarthi, Sri Harika, Sinha, Garima, Greco, Steven J., Rameshwar, Pranela
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395452/
https://ncbi.nlm.nih.gov/pubmed/30853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00134
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