Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

Glioblastoma multiforme (GBM), the most common and lethal tumor of the adult brain, generally shows chemo- and radioresistance. MicroRNAs (miRs) regulate physiological processes, such as resistance of GBM cells to temozolomide (TMZ). Although miRs are attractive targets for cancer therapeutics, the...

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Detalhes bibliográficos
Main Authors: Munoz, Jessian L, Bliss, Sarah A, Greco, Steven J, Ramkissoon, Shakti H, Ligon, Keith L, Rameshwar, Pranela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027430/
https://ncbi.nlm.nih.gov/pubmed/24084846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.60
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