Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo

Streptococcus pyogenes is a major human pathogen causing a variety of diseases ranging from common pharyngitis to life-threatening soft tissue infections and sepsis. Microbial nucleic acids, especially bacterial RNA, have recently been recognized as a major group of pathogen-associated molecular pat...

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Udgivet i:Front Immunol
Main Authors: Hafner, Anna, Kolbe, Ulrike, Freund, Isabel, Castiglia, Virginia, Kovarik, Pavel, Poth, Tanja, Herster, Franziska, Weigand, Markus A., Weber, Alexander N. R., Dalpke, Alexander H., Eigenbrod, Tatjana
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394247/
https://ncbi.nlm.nih.gov/pubmed/30846984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00198
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