Crystal structure of the Redβ C-terminal domain in complex with λ Exonuclease reveals an unexpected homology with λ Orf and an interaction with Escherichia coli single stranded DNA binding protein

Bacteriophage λ encodes a DNA recombination system that includes a 5′-3′ exonuclease (λ Exo) and a single strand annealing protein (Redβ). The two proteins form a complex that is thought to mediate loading of Redβ directly onto the single-stranded 3′-overhang generated by λ Exo. Here, we present a 2...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Caldwell, Brian J, Zakharova, Ekaterina, Filsinger, Gabriel T, Wannier, Timothy M, Hempfling, Jordan P, Chun-Der, Lee, Pei, Dehua, Church, George M, Bell, Charles E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393309/
https://ncbi.nlm.nih.gov/pubmed/30624736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1309
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