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Minor Isozymes Tailor Yeast Metabolism to Carbon Availability

Isozymes are enzymes that differ in sequence but catalyze the same chemical reactions. Despite their apparent redundancy, isozymes are often retained over evolutionary time, suggesting that they contribute to fitness. We developed an unsupervised computational method for identifying environmental co...

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Bibliographische Detailangaben
Veröffentlicht in:mSystems
Hauptverfasser: Bradley, Patrick H., Gibney, Patrick A., Botstein, David, Troyanskaya, Olga G., Rabinowitz, Joshua D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392091/
https://ncbi.nlm.nih.gov/pubmed/30834327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00170-18
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