Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages

Glucocorticoid receptor is a transcription factor that is ubiquitously expressed. Glucocorticoids are circadian steroids that regulate a wide range of bodily functions, including immunity. Here we report that synthetic glucocorticoids affect 1035 mRNAs in isolated healthy human blood monocytes but o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Cheng, Nanni, Luca, Novakovic, Boris, Megchelenbrink, Wout, Kuznetsova, Tatyana, Stunnenberg, Hendrik G., Ceri, Stefano, Logie, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6391480/
https://ncbi.nlm.nih.gov/pubmed/30809020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39395-9
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