Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor α and glucocorticoid induced apoptosis

BACKGROUND: Glucocorticoids (GCs) are commonly used in the treatment of (chronic) inflammatory diseases and cancer, but inherent or acquired resistance to these drugs limits their optimal efficacy. The availability of drugs that could modulate GC resistance is therefore of potential clinical interes...

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Detalhes bibliográficos
Main Authors: Oerlemans, Ruud, Vink, Josefien, Dijkmans, Ben A C, Assaraf, Yehuda G, van Miltenburg, Marjolein, van der Heijden, Joost, Ifergan, Ilan, Lems, Willem F, Scheper, Rik J, Kaspers, Gertjan J L, Cloos, Jacqueline, Jansen, Gerrit
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994309/
https://ncbi.nlm.nih.gov/pubmed/17267514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.060509
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