Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes

Gene expression is generally regulated by recruitment of transcription factors and RNA polymerase II (RNAP II) to specific sequences in the gene promoter region. The Integrator complex mediates processing of small nuclear RNAs (snRNAs) as well as the initiation and release of paused RNAP II at speci...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Gómez-Orte, Eva, Sáenz-Narciso, Beatriz, Zheleva, Angelina, Ezcurra, Begoña, de Toro, María, López, Rosario, Gastaca, Irene, Nilsen, Hilde, Sacristán, María P., Schnabel, Ralf, Cabello, Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390993/
https://ncbi.nlm.nih.gov/pubmed/30807579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007981
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