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Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes

Gene expression is generally regulated by recruitment of transcription factors and RNA polymerase II (RNAP II) to specific sequences in the gene promoter region. The Integrator complex mediates processing of small nuclear RNAs (snRNAs) as well as the initiation and release of paused RNAP II at speci...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Gómez-Orte, Eva, Sáenz-Narciso, Beatriz, Zheleva, Angelina, Ezcurra, Begoña, de Toro, María, López, Rosario, Gastaca, Irene, Nilsen, Hilde, Sacristán, María P., Schnabel, Ralf, Cabello, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390993/
https://ncbi.nlm.nih.gov/pubmed/30807579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007981
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