In vivo evidence for pre‐symptomatic neuroinflammation in a MAPT mutation carrier

Neuroinflammation occurs in frontotemporal dementia, however its timing relative to protein aggregation and neuronal loss is unknown. Using positron emission tomography and magnetic resonance imaging to quantify these processes in a pre‐symptomatic carrier of the 10 + 16 MAPT mutation, we show micro...

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Bibliografiska uppgifter
I publikationen:Ann Clin Transl Neurol
Huvudupphovsmän: Bevan‐Jones, W. Richard, Cope, Thomas E., Jones, P. Simon, Passamonti, Luca, Hong, Young T., Fryer, Tim, Arnold, Robert, Coles, Jonathan P., Aigbirhio, Franklin I., O'Brien, John T., Rowe, James B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Brief Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389753/
https://ncbi.nlm.nih.gov/pubmed/30847369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.683
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