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CFTR dysfunction increases endoglin and TGF‐β signaling in airway epithelia
Endoglin (ENG) regulates signaling by transforming growth factor‐β (TGF‐β), a genetic modifier of cystic fibrosis (CF) lung disease severity. We hypothesized that ENG mediates TGF‐β pathobiology in CF airway epithelia. Comparing CF and non‐CF human lungs, we measured ENG by qPCR, immunoblotting and...
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| 發表在: | Physiol Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6389738/ https://ncbi.nlm.nih.gov/pubmed/30806029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13977 |
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