RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer’s Associated Cognitive Deficits

BACKGROUND: Although synaptic impairment is prerequisite to cognitive deficiencies in Alzheimer’s disease (AD), mechanisms underlying the dysregulation of essential synaptic scaffolding components and their integrity remain elusive. RPS23RG1 is a newly identified protein implicated in AD. However, t...

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Publicado en:Biol Psychiatry
Main Authors: Zhao, Dongdong, Meng, Jian, Zhao, Yingjun, Huo, Yuanhui, Liu, Yan, Zheng, Naizhen, Zhang, Muxian, Gao, Yue, Chen, Zhicai, Sun, Hao, Wang, Xiangyu, Jing, Chuya, Zhang, Tongmei, Zhang, Xian, Luo, Hong, Wang, Xin, Zhang, Jie, Liu, Fa-rong, Li, Yanfang, Bu, Guojun, Wen, Lei, Huang, Timothy Y., Xu, Huaxi, Zhang, Yun-wu
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389446/
https://ncbi.nlm.nih.gov/pubmed/30292394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.08.009
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