RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits

Alzheimer’s disease (AD) is the most common form of dementia in the elderly. It is generally believed that β-amyloidogenesis, tau-hyperphosphorylation, and synaptic loss underlie cognitive decline in AD. Rps23rg1, a functional retroposed mouse gene, has been shown to reduce Alzheimer’s β-amyloid (Aβ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yan, Li, Chen, Yaomin, Li, Wubo, Huang, Xiumei, Badie, Hedieh, Jian, Fan, Huang, Timothy, Zhao, Yingjun, Cohen, Stanley N., Li, Limin, Zhang, Yun-wu, Luo, Huanmin, Tu, Shichun, Xu, Huaxi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702092/
https://ncbi.nlm.nih.gov/pubmed/26733416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18668
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