Resolvin D1, but not Resolvin E1, Transactivates the Epidermal Growth Factor Receptor to Increase Intracellular Calcium and Glycoconjugate Secretion in Rat and Human Conjunctival Goblet Cells

PURPOSE: To identify interactions of the epidermal growth factor receptor (EGFR) with the pro-resolving mediator receptors for RvD1 and RvE1 to stimulate an increase in intracellular [Ca(2+)] ([Ca(2+)](i)) and mucin secretion from cultured human and rat conjunctival goblet cells. METHODS: Goblet cel...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Kaye, Rebecca, Botten, Nora, Lippestad, Marit, Li, Dayu, Hodges, Robin R., Utheim, Tor P., Serhan, Charles N., Dartt, Darlene A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389367/
https://ncbi.nlm.nih.gov/pubmed/30513286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.11.018
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