A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity

BACKGROUND: The current BCG vaccine induces only short-term protection against Mycobacterium tuberculosis (Mtb), suggesting its failure to generate long-lasting memory T cells. Previously, we have demonstrated that a self-adjuvanting peptide of Mtb (L91), successfully generated enduring memory Th1 c...

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Vydáno v:J Transl Med
Hlavní autoři: Rai, Pradeep K., Chodisetti, Sathi Babu, Zeng, Weiguang, Nadeem, Sajid, Maurya, Sudeep K., Pahari, Susanta, Janmeja, Ashok K., Jackson, David C., Agrewala, Javed N.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389088/
https://ncbi.nlm.nih.gov/pubmed/28985739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1301-x
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