Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation

BACKGROUND: Inflammatory stimuli induce the hepatic iron regulatory hormone hepcidin, which contributes to anaemia of inflammation (AI). Hepcidin expression is regulated by the bone morphogenetic protein (BMP) and the interleukin-6 (IL-6) signalling pathways. Prior results indicate that the BMP type...

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Bibliografiske detaljer
Udgivet i:BMC Physiol
Main Authors: Gallitz, Inka, Lofruthe, Niklas, Traeger, Lisa, Bäumer, Nicole, Hoerr, Verena, Faber, Cornelius, Kuhlmann, Tanja, Müller-Tidow, Carsten, Steinbicker, Andrea U.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389079/
https://ncbi.nlm.nih.gov/pubmed/29482530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12899-018-0037-z
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