DNA methylation-mediated Klotho silencing is an independent prognostic biomarker of head and neck squamous carcinoma

PURPOSE: To study the prognostic value of klotho (KL) and its promoter DNA methylation in head and neck squamous cell carcinoma (HNSCC) and to assess their associations with the autophagy gene LC3 and the RNA transferase gene NSUN2. MATERIALS AND METHODS: Upper quartile normalized RNA-seq V2 RSEM va...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Manag Res
Asıl Yazarlar: Zhu, Yun, Cao, Xuehong, Zhang, Xiaomeng, Chen, Quan, Wen, Lei, Wang, Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388988/
https://ncbi.nlm.nih.gov/pubmed/30863149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S188415
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