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DNA methylation-mediated Klotho silencing is an independent prognostic biomarker of head and neck squamous carcinoma

PURPOSE: To study the prognostic value of klotho (KL) and its promoter DNA methylation in head and neck squamous cell carcinoma (HNSCC) and to assess their associations with the autophagy gene LC3 and the RNA transferase gene NSUN2. MATERIALS AND METHODS: Upper quartile normalized RNA-seq V2 RSEM va...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Zhu, Yun, Cao, Xuehong, Zhang, Xiaomeng, Chen, Quan, Wen, Lei, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388988/
https://ncbi.nlm.nih.gov/pubmed/30863149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S188415
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