PNUTS mediates ionizing radiation-induced CNE-2 nasopharyngeal carcinoma cell migration, invasion, and epithelial–mesenchymal transition via the PI3K/AKT signaling pathway

PURPOSE: Ionizing radiation (IR) is widely used for treating nasopharyngeal carcinoma (NPC). However, recent studies indicate that IR can also promote the migration and invasion of malignant tumors. Phosphatase 1 nuclear-targeting subunit (PNUTS), a novel interacting protein, was recently demonstrat...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Yu, Dan, An, Xiang, Fan, Wanlin, Wang, Xin, He, Yuxing, Li, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388972/
https://ncbi.nlm.nih.gov/pubmed/30863088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S188571
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