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Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells

TEMPO (2, 2, 6, 6-tetramethylphiperidine-1-oxyl) and its derivatives are stable free radical nitroxides widely used in the field of chemistry, biology, and pharmacology. TEMPO was previously found to be mutagenic and to induce micronuclei in mammalian cells. In this study, we investigated and quanti...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Guo, Xiaoqing, Seo, Ji-Eun, Bryce, Steven M., Tan, Jenna A., Wu, Qiangen, Dial, Stacey L., Moore, Martha M., Mei, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388407/
https://ncbi.nlm.nih.gov/pubmed/29385624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy022
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