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Systematic discovery of anti-phage defense systems in the microbial pan-genome
The arms race between bacteria and phages led to the development of sophisticated anti-phage defense systems, including CRISPR-Cas and restriction-modification systems. Evidence suggests that unknown defense systems are located in “defense islands” in microbial genomes. We comprehensively characteri...
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| Publicado en: | Science |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6387622/ https://ncbi.nlm.nih.gov/pubmed/29371424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar4120 |
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