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Systematic discovery of anti-phage defense systems in the microbial pan-genome

The arms race between bacteria and phages led to the development of sophisticated anti-phage defense systems, including CRISPR-Cas and restriction-modification systems. Evidence suggests that unknown defense systems are located in “defense islands” in microbial genomes. We comprehensively characteri...

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Vydáno v:Science
Hlavní autoři: Doron, Shany, Melamed, Sarah, Ofir, Gal, Leavitt, Azita, Lopatina, Anna, Keren, Mai, Amitai, Gil, Sorek, Rotem
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387622/
https://ncbi.nlm.nih.gov/pubmed/29371424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar4120
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