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Systematic discovery of anti-phage defense systems in the microbial pan-genome
The arms race between bacteria and phages led to the development of sophisticated anti-phage defense systems, including CRISPR-Cas and restriction-modification systems. Evidence suggests that unknown defense systems are located in “defense islands” in microbial genomes. We comprehensively characteri...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6387622/ https://ncbi.nlm.nih.gov/pubmed/29371424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar4120 |
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