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vi-HMM: a novel HMM-based method for sequence variant identification in short-read data

BACKGROUND: Accurate and reliable identification of sequence variants, including single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (INDELs), plays a fundamental role in next-generation sequencing (NGS) applications. Existing methods for calling these variants often make sim...

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發表在:Hum Genomics
Main Authors: Tang, Man, Hasan, Mohammad Shabbir, Zhu, Hongxiao, Zhang, Liqing, Wu, Xiaowei
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387560/
https://ncbi.nlm.nih.gov/pubmed/30795817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0194-6
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