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Investigating bisulfite short-read mapping failure with hairpin bisulfite sequencing data
BACKGROUND: DNA methylation is an important epigenetic mark relevant to normal development and disease genesis. A common approach to characterizing genome-wide DNA methylation is using Next Generation Sequencing technology to sequence bisulfite treated DNA. The short sequence reads are mapped to the...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652484/ https://ncbi.nlm.nih.gov/pubmed/26576456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S11-S2 |
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