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Dynamic Characterization of the Human Heme Nitric Oxide/Oxygen (HNOX) Domain under the Influence of Diatomic Gaseous Ligands

Soluble guanylate cyclase (sGC) regulates numerous physiological processes. The β subunit Heme Nitric Oxide/Oxygen (HNOX) domain makes this protein sensitive to small gaseous ligands. The structural basis of the activation mechanism of sGC under the influence of ligands (NO, O(2), CO) is poorly unde...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Khalid, Rana Rehan, Siddiqi, Abdul Rauf, Mylonas, Efstratios, Maryam, Arooma, Kokkinidis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387030/
https://ncbi.nlm.nih.gov/pubmed/30736292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030698
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