The Obligate Intracellular Bacterium Orientia tsutsugamushi Targets NLRC5 To Modulate the Major Histocompatibility Complex Class I Pathway

Orientia tsutsugamushi is an obligate intracellular bacterium that infects mononuclear and endothelial cells to cause the emerging global health threat scrub typhus. The ability of O. tsutsugamushi to survive in monocytes facilitates bacterial dissemination to endothelial cells, which can subsequent...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Rodino, Kyle G., Adcox, Haley E., Martin, Rebecca K., Patel, Vaidehi, Conrad, Daniel H., Carlyon, Jason A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386551/
https://ncbi.nlm.nih.gov/pubmed/30559222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00876-18
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