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PML recruits TET2 to regulate DNA modification and cell proliferation in response to chemotherapeutic agent
Aberrant DNA methylation plays a critical role in the development and the progression of cancer. Failure to demethylate and to consequently reactivate methylation-silenced genes in cancer contributes to chemotherapeutic resistance, yet the regulatory mechanisms of DNA demethylation in response to ch...
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| 出版年: | Cancer Res |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6386530/ https://ncbi.nlm.nih.gov/pubmed/29735542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3091 |
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