The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit

Paramyxoviruses can establish persistent infections both in vitro and in vivo, some of which lead to chronic disease. However, little is known about the molecular events that contribute to the establishment of persistent infections by RNA viruses. Using parainfluenza virus type 5 (PIV5) as a model w...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Young, Dan F., Wignall-Fleming, Elizabeth B., Busse, David C., Pickin, Matthew J., Hankinson, Jacqueline, Randall, Elizabeth M., Tavendale, Amy, Davison, Andrew J., Lamont, Douglas, Tregoning, John S., Goodbourn, Steve, Randall, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386407/
https://ncbi.nlm.nih.gov/pubmed/30742688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007561
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