Network-guided prediction of aromatase inhibitor response in breast cancer

Prediction of response to specific cancer treatments is complicated by significant heterogeneity between tumors in terms of mutational profiles, gene expression, and clinical measures. Here we focus on the response of Estrogen Receptor (ER)+ post-menopausal breast cancer tumors to aromatase inhibito...

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Udgivet i:PLoS Comput Biol
Main Authors: Ruffalo, Matthew, Thomas, Roby, Chen, Jian, Lee, Adrian V., Oesterreich, Steffi, Bar-Joseph, Ziv
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386390/
https://ncbi.nlm.nih.gov/pubmed/30742607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006730
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