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Cryo-EM snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine
The spliceosome excises introns from pre-messenger RNAs using an RNA-based active site cradled by a dynamic protein scaffold. A recent revolution in cryo-electron microscopy has led to near-atomic structures of key spliceosome complexes, which provide insight into the mechanism of activation, splice...
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| Izdano u: | Nat Struct Mol Biol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6386135/ https://ncbi.nlm.nih.gov/pubmed/28981077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3463 |
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