ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations

The ADAMTS9 rs4607103 C allele is one of the few gene variants proposed to increase the risk of type 2 diabetes through an impairment of insulin sensitivity. We show that the variant is associated with increased expression of the secreted ADAMTS9 and decreased insulin sensitivity and signaling in hu...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Diabetes
Asıl Yazarlar: Graae, Anne-Sofie, Grarup, Niels, Ribel-Madsen, Rasmus, Lystbæk, Sara H., Boesgaard, Trine, Staiger, Harald, Fritsche, Andreas, Wellner, Niels, Sulek, Karolina, Kjolby, Mads, Backe, Marie Balslev, Chubanava, Sabina, Prats, Clara, Serup, Annette K., Birk, Jesper B., Dubail, Johanne, Gillberg, Linn, Vienberg, Sara G., Nykjær, Anders, Kiens, Bente, Wojtaszewski, Jørgen F.P., Larsen, Steen, Apte, Suneel S., Häring, Hans-Ulrich, Vaag, Allan, Zethelius, Björn, Pedersen, Oluf, Treebak, Jonas T., Hansen, Torben, Holst, Birgitte
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2019
Konular:
Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385758/
https://ncbi.nlm.nih.gov/pubmed/30626608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0418
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller