Loss of Nuclear and Membrane Estrogen Receptor-α Differentially Impairs Insulin Secretion and Action in Male and Female Mice

Estrogens favor glucose homeostasis primarily through the estrogen receptor-α (ERα), but the respective importance of nuclear ERα (NOER) and membrane ERα (MOER) pools to glucose homeostasis are unknown. We studied glucose homeostasis, insulin secretion, and insulin sensitivity in male and female mic...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Allard, Camille, Morford, Jamie J., Xu, Beibei, Salwen, Benjamin, Xu, Weiwei, Desmoulins, Lucie, Zsombok, Andrea, Kim, Jason K., Levin, Ellis R., Mauvais-Jarvis, Franck
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2019
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385757/
https://ncbi.nlm.nih.gov/pubmed/30305367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0293
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