Clusterin Impairs Hepatic Insulin Sensitivity and Adipocyte Clusterin Associates With Cardiometabolic Risk

OBJECTIVE: Components of the adipose tissue (AT) extracellular matrix (ECM) are recently discovered contributors to obesity-related cardiometabolic disease. We identified increased adipocyte expression of ECM-related clusterin (apolipoprotein J) in obese versus lean women by microarray. Our objectiv...

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Détails bibliographiques
Publié dans:Diabetes Care
Auteurs principaux: Bradley, David, Blaszczak, Alecia, Yin, Zheng, Liu, Joey, Joseph, Joshua J., Wright, Valerie, Anandani, Kajol, Needleman, Bradley, Noria, Sabrena, Renton, David, Yearsley, Martha, Wong, Stephen T.C., Hsueh, Willa A.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2019
Sujets:
Cardiovascular and Metabolic Risk
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385696/
https://ncbi.nlm.nih.gov/pubmed/30659075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0870
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