Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARγ/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats

BACKGROUND: Subarachnoid hemorrhage (SAH) is a life-threatening subtype of stroke with high mortality and disabilities. Retinoid X receptor (RXR) has been shown to be neuroprotective against ischemia/reperfusion injury. This study aimed to investigate the effects of the selective RXR agonist bexarot...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zuo, Yuchun, Huang, Lei, Enkhjargal, Budbazar, Xu, Weilin, Umut, Ocak, Travis, Zachary D., Zhang, Guangyu, Tang, Jiping, Liu, Fei, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385420/
https://ncbi.nlm.nih.gov/pubmed/30791908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1432-5
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