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Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer
Immunotherapy has only limited efficacy against pancreatic ductal adenocarcinoma (PDAC) due to the presence of an immunosuppressive tumor-associated stroma. Here, we demonstrate an effective modulation of that stroma by irreversible electroporation (IRE), a local ablation technique that has received...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6385305/ https://ncbi.nlm.nih.gov/pubmed/30796212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08782-1 |
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