Identification of Neutralizing Monoclonal Antibodies Targeting Novel Conformational Epitopes of the Porcine Epidemic Diarrhoea Virus Spike Protein

Since 2010, newly identified variants of porcine epidemic diarrhoea virus (PEDV) have caused high mortality in neonatal piglets which has devastated the swine industry. The spike (S) glycoprotein of PEDV contains multiple neutralizing epitopes and is a major target for PEDV neutralization and vaccin...

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發表在:Sci Rep
Main Authors: Chang, Chia-Yu, Cheng, Ivan-Chen, Chang, Yen-Chen, Tsai, Pei-Shiue, Lai, Seiu-Yu, Huang, Yu-Liang, Jeng, Chian-Ren, Pang, Victor Fei, Chang, Hui-Wen
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385244/
https://ncbi.nlm.nih.gov/pubmed/30792462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39844-5
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