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Identification of Neutralizing Monoclonal Antibodies Targeting Novel Conformational Epitopes of the Porcine Epidemic Diarrhoea Virus Spike Protein

Since 2010, newly identified variants of porcine epidemic diarrhoea virus (PEDV) have caused high mortality in neonatal piglets which has devastated the swine industry. The spike (S) glycoprotein of PEDV contains multiple neutralizing epitopes and is a major target for PEDV neutralization and vaccin...

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Publicado no:Sci Rep
Main Authors: Chang, Chia-Yu, Cheng, Ivan-Chen, Chang, Yen-Chen, Tsai, Pei-Shiue, Lai, Seiu-Yu, Huang, Yu-Liang, Jeng, Chian-Ren, Pang, Victor Fei, Chang, Hui-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385244/
https://ncbi.nlm.nih.gov/pubmed/30792462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39844-5
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