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Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis

In persons with cystic fibrosis (CF), decreased airway microbial diversity is associated with lower lung function. Conflicting data exist on the impact of short-term antibiotics for treatment of acute pulmonary exacerbations. However, whether differences in antibiotic exposure impacts airway microbi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hahn, Andrea, Fanous, Hani, Jensen, Caroline, Chaney, Hollis, Sami, Iman, Perez, Geovanny F., Koumbourlis, Anastassios C., Louie, Stan, Bost, James E., van den Anker, John N., Freishtat, Robert J., Zemanick, Edith T., Crandall, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385179/
https://ncbi.nlm.nih.gov/pubmed/30796252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38984-y
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