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pKa Determination of a Histidine Residue in a Short Peptide Using Raman Spectroscopy
Determining the pKa of key functional groups is critical to understanding the pH-dependent behavior of biological proteins and peptide-based biomaterials. Traditionally, (1)H NMR spectroscopy has been used to determine the pKa of amino acids; however, for larger molecules and aggregating systems, th...
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| Publicado no: | Molecules |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6385126/ https://ncbi.nlm.nih.gov/pubmed/30678032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030405 |
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