P-glycoprotein Inhibitor Tariquidar Potentiates Efficacy of Astragaloside IV in Experimental Autoimmune Encephalomyelitis Mice

ATP-binding cassette (ABC) transporters, such as P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), often reduce drug efficacy and are the major cause of drug resistance. Astragaloside IV (ASIV), one of the bioactive saponins isolated from Astragalus membranaceus, has been demonstrat...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Zhang, Wei, Liu, Mei, Yang, Liu, Huang, Fei, Lan, Yunyi, Li, Hongli, Wu, Hui, Zhang, Beibei, Shi, Hailian, Wu, Xiaojun
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384695/
https://ncbi.nlm.nih.gov/pubmed/30717494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030561
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