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Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates

BACKGROUND: The Asp358Ala variant (rs2228145; A>C) in the IL (interleukin)-6 receptor (IL6R) gene has been implicated in the development of abdominal aortic aneurysms (AAAs), but its effect on AAA growth over time is not known. We aimed to investigate the clinical association between the IL6R-Asp...

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Veröffentlicht in:Circ Genom Precis Med
Hauptverfasser: Paige, Ellie, Clément, Marc, Lareyre, Fabien, Sweeting, Michael, Raffort, Juliette, Grenier, Céline, Finigan, Alison, Harrison, James, Peters, James E., Sun, Benjamin B., Butterworth, Adam S., Harrison, Seamus C., Bown, Matthew J., Lindholt, Jes S., Badger, Stephen A., Kullo, Iftikhar J., Powell, Janet, Norman, Paul E., Scott, D. Julian A., Bailey, Marc A., Rose-John, Stefan, Danesh, John, Freitag, Daniel F., Paul, Dirk S., Mallat, Ziad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383754/
https://ncbi.nlm.nih.gov/pubmed/30657332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.118.002413
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