Impaired Autophagy in CD11b(+) Dendritic Cells Expands CD4(+) Regulatory T Cells and Limits Atherosclerosis in Mice

Atherosclerosis is a chronic inflammatory disease. Recent studies have shown that dysfunctional autophagy in endothelial cells, smooth muscle cells, and macrophages, plays a detrimental role during atherogenesis, leading to the suggestion that autophagy-stimulating approaches may provide benefit. OB...

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Vydáno v:Circ Res
Hlavní autoři: Clement, Marc, Raffort, Juliette, Lareyre, Fabien, Tsiantoulas, Dimitrios, Newland, Stephen, Lu, Yuning, Masters, Leanne, Harrison, James, Saveljeva, Svetlana, Ma, Marcella K.L., Ozsvar-Kozma, Maria, Lam, Brian Y.H., Yeo, Giles S.H., Binder, Christoph J., Kaser, Arthur, Mallat, Ziad
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844650/
https://ncbi.nlm.nih.gov/pubmed/31610723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.315248
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