Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo

EMT occurs in response to a number of stresses conditions as mechanical stretch, cancer, hypoxia, oxidative stress (ROS), among others. EMT describes a phenotypical change induced in epithelial cells. It is characterized by increases in motility, extracellular matrix synthesis, proliferation, and in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Convento, Marcia, Pessoa, Edson, Aragão, Alef, Schor, Nestor, Borges, Fernanda
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2019
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383687/
https://ncbi.nlm.nih.gov/pubmed/30800221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26634
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