Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo

EMT occurs in response to a number of stresses conditions as mechanical stretch, cancer, hypoxia, oxidative stress (ROS), among others. EMT describes a phenotypical change induced in epithelial cells. It is characterized by increases in motility, extracellular matrix synthesis, proliferation, and in...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Convento, Marcia, Pessoa, Edson, Aragão, Alef, Schor, Nestor, Borges, Fernanda
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383687/
https://ncbi.nlm.nih.gov/pubmed/30800221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26634
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